Research

aCRL®.Research topic

The aCRL®.academy Europe offers awareness training with aCRL®.colors and shapes in a personal and professional context. The current aCRL®.colors and shapes were developed in an optimization process and are subject to constant quality control. (see Fig. F1)

R&D projects are carried out in parallel to continuously review the aCRL® methods and tools as well as new applications. The following topics are currently the focus of attention:

  • Color analysis of the aCRL®.color cards in reflection:
    Development of the aCRL®. color standards
    Continuous quality control of aCRL®.colors
  • Transfer of subtractive color generation in color charts to
    additive color generation in monitors and screens (see Fig. F2)
  • Fundamental research on the interaction of light and tissue or cell cultures using fiber optics
  • Verification of the effectiveness of aCRL® methods and tools in diagnostics and therapy.

Team

kklein

Karl-Friedrich Klein

Prof. Dr.-Ing. Physics, Optics
Head of Research

eschulze

Eddi Schulze

M.Ed. Physics & Mathematics
aCRL® Development & Teaching

Color analysis of aCRL® color charts and quality control

Fig. F1: Measuring stations for color characterization and quality control, and typical measurement examples

aCRL®.colors and gray forms are subject to continuous quality control. A commercial color measuring device or a fiber optic color measuring prototype is used for analysis and documentation. The color values and the distances derived from them are measured to an aCRL®.standard.

Fig. F2: Representation of the possible center wavelengths of typical light-emitting diodes (LEDs) as a function of wavelength in the visible wavelength range and the attenuation curve of a polymer fiber, as of 2010 /1/

Interaction of light and tissue or cell cultures with fiber optics

In physiological research on tissues and cells, Ca²⁺, NADH, FAD, ATPase activity, or membrane potential, as well as their temporal changes during stretching, can be detected using fluorescence detection via a fiber optic UV probe. (see Figures F3 and F4). Conversely, this system can be used to directly investigate the effect of force at different aCRL®.primary and secondary colors.

Fig. F3: Arrangement for measuring the fluorescence of tissue that is moved by micromanipulators with nano-forces /3/

Fig. F4: Fiber optic prototype with a special arrangement of optical fibers for controlled light detection /3/

References

/1/ LED prototype for teaching in the field of fiber optics, developed by POFAC at Nuremberg Tech

/2/ M. Brandenburger, J. Wenzel, R. Bogdan, D. Richardt, F. Nguemo, M. Reppel, J. Hescheler, H. Terlau, A. Dendorfer, “Organotypic slice culture from human adult ventricular myocardium,” Cardiovasc Res. 93(1), 50-9 (2012).

/3/ M. Belz, A. Dendorfer, J. Werner, D. Lambertz, K.-F. Klein: “Fiber Optic Biofluorometer for Physiological Research on Muscle Slices”; Proc. of SPIE Vol. 9702, 97020Q (San Francisco, Jan. 2016)